Improved sensitivity for ESI and MALDI-TOF mass spec analysis
Modifying glycan fragmentation patterns during MSn analysis
LudgerTag Glycan Labeling Kits LudgerTag kit reagents are purified to analytical grade and are dispensed and sealed under clean, inert atmospheres. The ampoules are pre-cleaned by pyrolysis at 500°C then opened just before dispensing and sealing under oxygen-free dry nitrogen. These controls ensure that your analyses work properly each and every time.
Acetic Acid Promotes acid catalyzed ring opening of the glycan reducing terminus prior to the formation of an imine intermediate between the sugars and the unprotonated form of the dye.
The comprehensive range of LudgerTag dyes include 2-AB, 2-AA, Procainamide, DMB, and AA-Ac to cover different types of glycoanalyses by HPLC and MS.
An anhdrous solvent used to dissolve all the components of the reductive amination labeling reaction.
Sodium Cyanoborohydride or Non-Toxic 2PB
This reductant stabilizes the imine produced by the reaction of the dye and glycans to produce stable fluorescently labeled glycans.